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Antidepressants Not Recommended for Autism
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MedpageToday.com REPORTS HERE "selective serotonin reuptake inhibitors (SSRIs) can't be recommended for treating autism in children or adults at this point, according to a Cochrane review. The antidepressants have shown emerging evidence of harm without any benefit in pediatric cases, reported Katrina Williams, PhD, of the University of New South Wales and Sydney Children's Hospital in Sydney, Australia, and colleagues in the Cochrane Library."

"In adult cases, two small studies have shown improvements in overall symptoms and obsessive-compulsive behavior along with aggression in one and anxiety in the other. However, this limited evidence in adults is not yet sufficiently robust for clinicians to rely on, Williams' group cautioned."

"Antidepressants have become one of the most commonly prescribed psychotropic medications for autism spectrum disorders and the class for which prescribing has risen most."

"The drugs used in these seven trials were fluoxetine (Prozac) in two, fluvoxamine (Luvox) in two, fenfluramine (Pondimin, removed from the U.S. market in 1997) in two, and citalopram (Celexa) in one."

"Adverse events in children were significantly elevated with citalopram and fluvoxamine (in one of three trials). Citalopram was also linked to a severe case of seizures that persisted after withdrawal from the drug. Fenfluramine in children was associated with weight loss overall, two cases of increased withdrawal and sadness, and two cases of increased stereotypies."

 
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U.S. government overpaid private insurance companies administering Medicare Advantage plans by as much as $3.1 billion in 2010, according to a new report from the Government Accountability Office (GAO).

About a quarter of all Medicare beneficiaries are enrolled in Medicare Advantage plans, and the Centers for Medicare and Medicaid Services (CMS) paid about $114 billion to the plans in 2010.


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