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Medpagetoday.com REPORTS HERE that "preoperative aspirin therapy was associated with a host of beneficial effects spanning several organ systems, according to a large observational study."

"This study provides new evidence that preoperative aspirin therapy (versus no preoperative aspirin) is associated with a significant decrease in risk of 30 day mortality (3.5% versus 6.5%), renal failure (3.7% versus 7.1%), dialysis required (1.9% versus 3.6%), ICU stay (average 107.2 hours versus 136.1), and a composite outcome -- MACE (8.7% versus 10.8%); and is not associated with increased risk of readmissions (14.5% versus 12.8%)."

"Moreover, aspirin was beneficial even though patients taking preoperative aspirin were significantly older and had more comorbidities than those not taking aspirin."

"Taken together, preoperative aspirin seems to have efficacy in the face of the 'most important confounding factors -- comorbidities' in these high-risk patients ...."

"Previous studies have found a benefit for early postoperative aspirin therapy after coronary artery bypass graft (CABG) surgery, but evidence supporting the role of preoperative aspirin therapy was less consistent."

"The investigators wrote that the Society of Thoracic Surgeons and the European Association for Cardio-Thoracic Surgery recommend discontinuation of aspirin several days prior to cardiac surgery, which also had been the recommendation of the American College of Cardiology (ACC) and the American Heart Association (AHA)."

"However, in updated guidelines released in November, the ACC and AHA now recommend preoperative aspirin before CABG surgery."

 
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FeaturedNews
Clinical Trial Data Should Be Open for Review
Published 04/30/2012 - 3:14 p.m.  CDT

Original clinical study reports, which contain far more detail than published randomized trials, should be made available to independent researchers seeking to verify efficacy and safety claims.

In support of this argument, the history of the influenza antiviral oseltamivir (Tamiflu), which was approved by the FDA in 1999, was cited. The widespread belief in oseltamivir's efficacy, was based on a meta-analysis of 10 trials conducted by the manufacturer prior to licensure.  But the authors pointed out that the FDA, which was aware of these clinical trials, concluded that oseltamivir had not been shown to reduce complications and required a statement on the drug's label to that effect.  Moreover, oseltamivir was not given an FDA indication for prevention of spread of influenza.

To this, [authors] commented, "If FDA is right, the drug's effectiveness may be no better than aspirin or acetaminophen.'"
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HR 329 in need of Co Sponsors
Published 04/30/2012 - 11:11 a.m.  CDT

Representative Bob Filner recently introduced the Chiropractic Care to All Veterans Act (H.R. 329). The bill would require the Veterans Administration (VA) to have a chiropractic physician on staff at all major VA medical facilities by 2014. You too can help ensure chiropractic care is available to those who have placed their lives in service to our country. H.R. 329 is in need of cosponsors to assist its likelihood of passage.

CLICK HERE to urge your legislators to cosponsor the bill.
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Court Sides with Generic-Drug Makers
Published 04/25/2012 - 6:33 a.m.  CDT

In a unanimous decision, the Supreme Court ruled that generic drugmaker Caraco Pharmaceutical Laboratories can sue Novo Nordisk for what Caraco says are exaggerated descriptions of the scope of patents Novo Nordisk holds on a diabetes drug.

A group of Democratic senators has introduced a bill that would allow people to sue generic drugmakers over failing to update their drug labels to include all known risks. The bill is meant to counter last year's Supreme Court decision in a generic drug dispute.
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Original clinical study reports, which contain far more detail than published randomized trials, should be made available to independent researchers seeking to verify efficacy and safety claims.

In support of this argument, the history of the influenza antiviral oseltamivir (Tamiflu), which was approved by the FDA in 1999, was cited. The widespread belief in oseltamivir's efficacy, was based on a meta-analysis of 10 trials conducted by the manufacturer prior to licensure.  But the authors pointed out that the FDA, which was aware of these clinical trials, concluded that oseltamivir had not been shown to reduce complications and required a statement on the drug's label to that effect.  Moreover, oseltamivir was not given an FDA indication for prevention of spread of influenza.

To this, [authors] commented, "If FDA is right, the drug's effectiveness may be no better than aspirin or acetaminophen.'"

The Kilgore College Small Business Development Center (SBDC) will sponsor an educational seminar for medical office staff, including office managers and billing staff, entitled Basic Workers’ Compensation for Medical Office Staff on Wednesday, May 2, 2012.

Representative Bob Filner recently introduced the Chiropractic Care to All Veterans Act (H.R. 329). The bill would require the Veterans Administration (VA) to have a chiropractic physician on staff at all major VA medical facilities by 2014. You too can help ensure chiropractic care is available to those who have placed their lives in service to our country. H.R. 329 is in need of cosponsors to assist its likelihood of passage.

CLICK HERE to urge your legislators to cosponsor the bill.

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Ethiopia and Kenya Trips.  Have you ever wanted to provide chiropractic care in another country and give back to those in need?

Dr. Teresa Jones has been volunteering on mission trips to Africa for 4 years and is reaching out to the District 5 for help this year. There are two chances to participate, both in July 2012 and if you are interested please RSVP to frontdesk@wholehealth-care.com to let her know you area interested!


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